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Patents And Applications

HCMS100 – Noninvasive tracking system to monitor group activity of lab animals

​The HCMS100 is a computerized, hands-off monitoring system of lab animals in their home-cage that allows objective observation with no animal interference. This system uses any standard cage racks retrofitted with a laser beam, enabling 24/7 noninvasive monitoring and analysing animal group activity including those of mice, hamsters, and rats.

 Patent applications for this technology have been filed.

 


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Therapeutic antibodies

​IIBR's Antibody engineering group developed several antibodies-based therapeutics against chemical and biological threat agents such as: Anthrax, Ricin, Organophosphates, Botulinum and Tularemia. Patent applications for these antibodies have been filed.​

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AF267B - drug development for Alzheimer disease

​IIBR's CNS team designed and developed AF267B and AF292 - a chemical molecules that can be used as a basis for the development of an ethical drug aiming to treat CNS neurodegenerative diseases including Alzheimer disease.

Currently, AF267B is in the early stages of Phase II study as part of drug development for Alzheimer disease.


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Animal Vaccines and recombinant antibodies for passive vaccination

​IIBR developed a vaccine for African Swine Fever (ASF). In addition, IIBR is in the process of developing a highly efficient recombinant antibodies for passive vaccination against Newcastle Disease in poultry.​

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“EVOXAC” - Ethical drug for Sjogren Syndrome

IIBR's CNS team, developed a chemical molecule that was used as a basis for the development of “EVOXAC" - an Ethical drug for the treatment of “Sjogren's Syndrome".

“EVOXAC" was approved by the FDA. ​



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Method developed for detection of exposure to ricin in clinical samples

​A highly sensitive method is required for detection of ricin in clinical samples. This unmet need, precludes therapeutic intervention in the case of suspected exposure to the toxin.​

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Development of novel nerve agents bio-scavengers based on long-lived recombinant AChE

​Nerve agents belong to a class of compounds known as organophosphate (OP) agents. OP nerve agents, such as sarin gas, soman, tabun or VX, enter the blood stream via inhalation or absorption through the skin.

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