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The National Reference Laboratory for Rickettsiosis, Ehrlichiosis and Leptospirosis Diseases

  • The National Reference Laboratories for Rickettsiosis, ​Ehrlichiosis and Leptospirosis Diseases at the IIBR are responsible for diagnosis of these diseases​ in clinical samples from patients from Israel's hospitals and clinics. 

  • The labs use robust serological and genetic methodologies for the accurate and sensitive detection of pathogens. The main techni​ques that are the indirect ImmunoFluorescence Assay (IFA) for Rickettsiosis and Micro Agglutination Test (MAT) for Leptospirosis, which are considered the gold standard tests.   

  • The lab has developed vast expertise in isolation and cultivation of these pathogens from a variety of clinical samples. 

During the summer of 2002, we investigated an outbreak of leptospirosis that involved IDF troops who participated in a military exercise near the Jordan River in northern Israel. Suspected cases were tested and diagnosed as positive. Due to the quick identification, all the patients fully recovered. 

pic901.jpg ​A scanning electron micrograph of a chemically-fixed Leptospira interrogans.​