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Pharmacology and Toxicology      
IIBR's advanced R&D projects in life sciences are supported by a wide variety of laboratories studying pharmacology, toxicology, physiology, clinical biochemistry, histology, as well as animal and human behavior. Scientists in the Department of Pharmacology specialize in neurosciences, cardiovascular and pulmonary research, ocular and dermal therapy. Inter-disciplinary projects are encouraged and frequently performed.

Research activities include:
  • Treatment and therapy of the effects caused by toxic compounds used in agriculture and industry;
  • Prevention, treatment and therapy of the effects caused by chemical and thermal burns;
  • Ocular studies of chemical and physical injuries to the cornea and retina, and their prevention and treatment;
  • Physiological studies of seizure activity and prevention of the resulting irreversible brain damage;
  • Stress mechanisms and preventive therapeutic means against aging and stress- induced neuronal damage;
  • Investigation of inflammatory modulators using ex vivo and tissue-culture methods;
  • Pharmacokinetic studies and investigation of drug delivery systems;
  • Drug-receptor interactions and physiological responses mediated by distinct neurotransmitter receptor sub-types




Performance in Behavioral Studies

Computerized test batteries were developed and validated to monitor behavioral changes following the use of therapeutic drugs, physical or environmental stress, neurological damage, etc. The systems are based on tests probing psychological processes such as perception, attention, memory, reasoning, time estimation, psychomotor functions, planning, situation assessment, decision making, problem solving, and communication, with emphasis on visual performance.

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