The IIBR biotechnology and genetic engineering teams offer extensive professional skills in production of native and recombinant proteins in highly efficient cell culture expression systems.
Customized R&D services for generation of cellderived products include:
- Generation of human or mammalian cell clones, exhibiting consistent high production / secretion of the protein of interest over a long period of time as well as favored post-translation processing.
- Evaluation of recombinant producer cells, serving as candidates for highlevel protein production in appropriate bacterial systems or established eukaryotic cells.
- Development of efficient cultivation systems of mammalian, anchorage-dependent cells in surface propagators, fixed-bed reactors, and stirred microcarrier cultures.
- Development of batch, fed batch, and perfusion cultures of suspended cells in large-scale bioreactors according to cGMP regulations.
|
| |
|
|